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MLT-747 Size:Contact [email protected] for quotation reversible and cell-permeable inhibitor of

SKU: 39266135612

4.5
USD119.00 USD161.00

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Description

reversible and cell-permeable inhibitor of Jumonji AT-Rich Interactive Domain 1 (JARID1) histone demethylases

PUMA and BAX

5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide

Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637)

MLT-747 Size:Contact [email protected] for quotation reversible and cell-permeable inhibitor ofMLT 747 is a potent, selective, allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 14 nM. Product information CAS Number: 2097853 86 4 Molecular Weight: 478. 33 Formula: C20H21Cl2N7O3 Chemical Name: 1 [5 chloro 6 (pyrrolidine 1 carbonyl)pyridin 3 yl] 3 {2 chloro 7 [(1S) 1 methoxyethyl]pyrazolo[1,5 a]pyrimidin 6 yl}urea Smiles: CO[C@@H](C)C1=C(C=NC2=CC(Cl)=NN21)NC(=O)NC1=CN=C(C(Cl)=C1)C(=O)N1CCCC1 InChiKey:

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